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Package: r-catalyst @ 1.20.1

Synopsis

Cytometry data analysis tools

Description

This package is Cytometry dATa anALYSis Tools (CATALYST). Mass cytometry like Cytometry by time of flight (CyTOF) uses heavy metal isotopes rather than fluorescent tags as reporters to label antibodies, thereby substantially decreasing spectral overlap and allowing for examination of over 50 parameters at the single cell level. While spectral overlap is significantly less pronounced in CyTOF than flow cytometry, spillover due to detection sensitivity, isotopic impurities, and oxide formation can impede data interpretability. CATALYST was designed to provide a pipeline for preprocessing of cytometry data, including:

  1. normalization using bead standards;

  2. single-cell deconvolution;

  3. bead-based compensation.

Home page
https://github.com/HelenaLC/CATALYST
Location
gnu/packages/bioconductor.scm (line: 14899, column: 2)
License

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