Language

Package: r-doubletfinder @ 2.0.3-1.554097b

Synopsis

Identify doublets in single-cell RNA sequencing data

Description

DoubletFinder identifies doublets by generating artificial doublets from existing scRNA-seq data and defining which real cells preferentially co-localize with artificial doublets in gene expression space. Other DoubletFinder package functions are used for fitting DoubletFinder to different scRNA-seq datasets. For example, ideal DoubletFinder performance in real-world contexts requires optimal pK selection and homotypic doublet proportion estimation. pK selection is achieved using pN-pK parameter sweeps and maxima identification in mean-variance-normalized bimodality coefficient distributions. Homotypic doublet proportion estimation is achieved by finding the sum of squared cell annotation frequencies.

Home page
https://github.com/chris-mcginnis-ucsf/DoubletFinder
Location
gnu/packages/bioinformatics.scm (line: 11365, column: 4)
License

Lint warnings

LinterMessageLocation
No lint warnings